The story takes place in Northern California in the spring of 2000, when the dot-com boom was at its peak. Elizabeth Reilly-Hayden is a successful executive in her late fifties and a divorced mother of two. Emotionally armored and living alone, she wants only to maintain the status quo: her long-term significant other, her job, and her trusted friends—five feisty women whose high school friendship has carried them through multiple marriages, dramatic divorces, and maddening menopause. Yet in a matter of days, the three anchors that have kept her moored are ripped away.